Directory of Open Access Journals – DOAJ
Most common TEAEs were headache (24%), nausea (17%), abdominal pain (12%), and nasopharyngitis (12%). Eight patients had serious TEAEs; 2 were fatal (unrelated to study treatment). Improved 6minute walking distance was observed from baseline to week 24: total mean (SD) change, + () meters; World Health Organization functional class was maintained or improved in 70% and 27% .